• 50 questions

NBME Psychiatry Shelf Practice Exam

Unofficial psychiatry shelf practice: short cases on psychosis, mood, anxiety, substance use, drug side effects and dementia.

The parents of a healthy 4-year-old boy are worried because he wets the bed about twice a week. He is dry during the day. What should they be told?

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Unofficial practice questions, not affiliated with NBME (the National Board of Medical Examiners). Bank checked October 12, 2026.

The real exam, as NBME describes it

Questions
110
Time limit
165 minutes
Physician task
Diagnosis, including foundational science concepts, 65 to 70%; pharmacotherapy, intervention and management 30 to 35%
Patient age
Birth to 12 in 10 to 15% of questions; 13 and older in 85 to 90%
Site of care
Ambulatory 60 to 65%, emergency department 20 to 30%, inpatient 5 to 10%

Checked October 12, 2026 against Psychiatry Subject Exam content outline and Subject Examination Timing Chart, nbme.org. Rules change, so confirm with the agency itself before your test.

NBME's own content outline

All 50 questions

General principles and the well patient 4

  • A 10-month-old girl cries and clings when her mother leaves the room, and she is wary of new people. She was not like this at 5 months. Growth and development are on track. What is the most likely explanation? MedlinePlus Medical Encyclopedia, "Separation anxiety in children", Causes; Treatment. Outline: NBME Psychiatry Subject Exam content outline, General Principles, Including Normal Age-Related Findings and Care of the Well Patient.
  • A 68-year-old woman is seen 3 weeks after her husband died. She has crying spells, sleeps poorly and gets less done at work. She has no thoughts of suicide. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Grief", Symptoms; Treatment. Outline: NBME Psychiatry Subject Exam content outline, General Principles, Including Normal Age-Related Findings and Care of the Well Patient.
  • A healthy 14-year-old boy comes for a well visit. He has no complaints. Which screening does the US Preventive Services Task Force recommend at his age? US Preventive Services Task Force, Depression and Suicide Risk in Children and Adolescents: Screening, Recommendation Summary. Outline: NBME Psychiatry Subject Exam content outline, General Principles, Including Normal Age-Related Findings and Care of the Well Patient.
  • The parents of a healthy 4-year-old boy are worried because he wets the bed about twice a week. He is dry during the day. What should they be told? MedlinePlus Medical Encyclopedia, "Bedwetting", opening; Causes. Outline: NBME Psychiatry Subject Exam content outline, General Principles, Including Normal Age-Related Findings and Care of the Well Patient.
Show all 50 questions (46 more)

Normal processes and psychosocial behaviors 2

  • A 34-year-old man has felt sad and tense since his divorce 6 weeks ago and is falling behind at work. He does not meet the criteria for another mental disorder. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Adjustment disorder", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: normal processes and psychosocial disorders/behaviors.
  • Which statement about sex and suicidal behavior matches the epidemiology? MedlinePlus Medical Encyclopedia, "Suicide and suicidal behavior", Causes. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: normal processes and psychosocial disorders/behaviors.

Psychotic disorders 4

  • A 22-year-old man has heard voices for 8 months. He has become isolated, shows little emotion and has left college. Medical tests are normal. Which treatment is most effective for his condition? MedlinePlus Medical Encyclopedia, "Schizophrenia", Treatment. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: psychotic disorders.
  • A 30-year-old woman has had delusions and hallucinations along with episodes of depression. Which finding supports schizoaffective disorder over a mood disorder with psychotic features? MedlinePlus Medical Encyclopedia, "Schizoaffective disorder", Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: psychotic disorders.
  • A 52-year-old woman with 6 weeks of low mood, weight loss and early waking now believes her organs are rotting. Which treatment is usually tried first? MedlinePlus Medical Encyclopedia, "Major depression with psychotic features", Treatment. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: psychotic disorders.
  • Three days after his brother died in a crash, a 28-year-old man becomes paranoid, hears voices and speaks incoherently. A drug screen is negative. Two weeks later he is back to normal. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Brief psychotic disorder", Causes; Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: psychotic disorders.

Anxiety disorders 4

  • A 19-year-old man washes his hands for 3 hours a day to quiet thoughts of contamination that he knows are excessive. In the talk therapy shown to work for this disorder, what does the patient do? MedlinePlus Medical Encyclopedia, "Obsessive-compulsive disorder", Treatment. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: anxiety disorders.
  • A 26-year-old woman has come to the emergency department four times with sudden chest pain, a pounding heart and fear of dying that peaks within minutes. Heart tests are normal. She now avoids being alone. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Panic disorder", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: anxiety disorders.
  • A 40-year-old man worries about money, work and his family's health on most days, with fatigue, irritability and restless sleep. How long must the worry have been present to fit generalized anxiety disorder? MedlinePlus Medical Encyclopedia, "Generalized anxiety disorder", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: anxiety disorders.
  • Two weeks after an armed robbery, a 31-year-old cashier has flashbacks and nightmares and avoids the store. Why is post-traumatic stress disorder not yet the diagnosis? MedlinePlus Medical Encyclopedia, "Post-traumatic stress disorder", Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: anxiety disorders.

Mood disorders 4

  • A 24-year-old man has slept 2 hours a night for a week, talks rapidly, has spent his savings and says he will be the next president. Which class of medicine is most often used first for his disorder? MedlinePlus Medical Encyclopedia, "Bipolar disorder", Causes; Treatment. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: mood disorders.
  • A 45-year-old woman has had a low mood on most days for 3 years, with low energy, poor self-esteem and poor concentration. She has kept working throughout. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Persistent depressive disorder", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: mood disorders.
  • Five days after giving birth, a 29-year-old woman is tearful, anxious and irritable. She is caring for and bonding with her baby and has no thoughts of harm. What is the most appropriate next step? MedlinePlus Medical Encyclopedia, "Postpartum depression", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: mood disorders.
  • For 3 years a 27-year-old woman has had swings between weeks of mild depression and weeks of high energy and elevated mood. She has never had a full manic or major depressive episode. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Cyclothymic disorder", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: mood disorders.

Somatic symptom and factitious disorders 3

  • A 3-year-old has been admitted six times for bloody urine that is never seen when his mother, a nurse, is away. Video shows her adding blood to a sample. Besides protecting the child, what is required? MedlinePlus Medical Encyclopedia, "Munchausen syndrome by proxy", Treatment. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: somatic symptoms and related disorders; factitious disorders.
  • A 35-year-old woman has had fatigue and widespread pain for 2 years and intense fear that they mean a deadly disease. Work-ups by five physicians were normal. Besides therapy, which plan is most appropriate? MedlinePlus Medical Encyclopedia, "Somatic symptom disorder", Treatment. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: somatic symptoms and related disorders; factitious disorders.
  • A 40-year-old man is sure he has colon cancer. He has no symptoms beyond occasional gas, two colonoscopies were normal, and he checks his abdomen daily. Reassurance helps for a few days. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Illness anxiety disorder", opening; Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: somatic symptoms and related disorders; factitious disorders.

Eating and impulse control disorders 3

  • A 13-year-old girl has patches of broken hair on her scalp. She describes rising tension that is relieved when she pulls hair out, and she cannot stop. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Trichotillomania", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: eating disorders and impulse control disorders.
  • A 17-year-old girl binges and then vomits. Which finding points to anorexia and away from bulimia? MedlinePlus Medical Encyclopedia, "Anorexia", Symptoms; "Bulimia", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: eating disorders and impulse control disorders.
  • A 19-year-old woman of normal weight has pitted tooth enamel, swollen cheeks and calluses over her knuckles. Which blood test result is most likely? MedlinePlus Medical Encyclopedia, "Bulimia", Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: eating disorders and impulse control disorders.

Disorders of infancy and childhood 3

  • A 2-year-old boy says no words, does not point or wave, and shows no pretend play. He repeats the same body movements over and over and is very upset when routines change. Hearing is normal. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Autism spectrum disorder", Symptoms; Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: disorders originating in infancy/childhood.
  • A 9-year-old boy has had eye blinking and shoulder shrugging many times a day for 18 months, and for the past year he has also made grunting sounds. He takes no medicine. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Tourette syndrome", Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: disorders originating in infancy/childhood.
  • For the past year an 8-year-old boy has argued with adults, refused requests, lost his temper and blamed others for his mistakes. He has not hurt people or animals, stolen or set fires. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Oppositional defiant disorder", Symptoms; "Conduct disorder", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: disorders originating in infancy/childhood.

Personality disorders 3

  • A 24-year-old woman has intense, unstable relationships. She sees people as all good or all bad, fears being abandoned and has injured herself several times. Which treatment has the main role? MedlinePlus Medical Encyclopedia, "Borderline personality disorder", Symptoms; Treatment. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: personality disorders.
  • A 32-year-old man in prison for fraud has lied, fought and broken the law for years and shows no remorse. Which history is required to diagnose antisocial personality disorder? MedlinePlus Medical Encyclopedia, "Antisocial personality disorder", Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: personality disorders.
  • A 38-year-old accountant redoes colleagues' work, insists on rigid rules and lists, and is sure his way is the correct one. He is not troubled by unwanted thoughts. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Obsessive-compulsive personality disorder", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: personality disorders.

Substance use disorders 3

  • A 27-year-old woman in jail since yesterday has muscle aches, yawning, tearing, a runny nose, goosebumps, diarrhea and dilated pupils. What is the most likely cause? MedlinePlus Medical Encyclopedia, "Opiate and opioid withdrawal", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: substance abuse disorders.
  • A 30-year-old man is found barely responsive with small pupils and 6 breaths a minute. Which medicine blocks the effect of the drug most likely involved? MedlinePlus Medical Encyclopedia, "Opioid intoxication", Symptoms; Treatment. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: substance abuse disorders.
  • A 54-year-old man who drinks heavily every day is admitted for emergency surgery. If delirium tremens develops, when do its symptoms most often begin? MedlinePlus Medical Encyclopedia, "Delirium tremens", Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: substance abuse disorders.

Adverse effects of drugs 4

  • A 33-year-old man with schizophrenia is started on clozapine. Which laboratory test is ordered regularly during treatment? MedlinePlus Drug Information, "Clozapine", Important Warning. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: adverse effects of drugs.
  • A 49-year-old woman who takes phenelzine has a sudden headache, a pounding heartbeat and sweating an hour after a meal of aged cheese and smoked fish. Which food component caused the reaction? MedlinePlus Drug Information, "Phenelzine", What special dietary instructions should I follow?. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: adverse effects of drugs.
  • A 58-year-old man who has taken an older antipsychotic for 12 years has repetitive chewing, tongue thrusting and piano-playing movements of his fingers. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Tardive dyskinesia", Causes; Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: adverse effects of drugs.
  • A 61-year-old woman with bipolar disorder has taken the same medicine for years. After a week of vomiting and poor fluid intake she has a coarse tremor, slurred speech and brisk reflexes. Which blood test is most useful now? MedlinePlus Medical Encyclopedia, "Lithium toxicity", opening; Symptoms; What to Expect at the Emergency Room. Outline: NBME Psychiatry Subject Exam content outline, Behavioral Health: adverse effects of drugs.

Nervous system 6

  • A 19-year-old student falls asleep in class despite sleeping all night. When he laughs hard, his knees buckle for a minute while he stays aware. Which brain chemical is often low in this disorder? MedlinePlus Medical Encyclopedia, "Narcolepsy", Causes; Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Nervous System & Special Senses.
  • A 41-year-old woman has depression, irritability and quick, sudden jerking movements of her arms and face. Her father had the same illness. What is the chance that each of her children inherits the gene? MedlinePlus Medical Encyclopedia, "Huntington disease", Causes. Outline: NBME Psychiatry Subject Exam content outline, Nervous System & Special Senses.
  • A 56-year-old man has made crude remarks to strangers and shoplifted over the past year. His memory is still good. MRI shows shrinkage of the frontal lobes. Which feature separates this dementia from Alzheimer disease? MedlinePlus Medical Encyclopedia, "Frontotemporal dementia", Causes; Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Nervous System & Special Senses.
  • A 72-year-old man has slowed thinking, new urinary incontinence and a gait in which his feet seem stuck to the floor. Head CT shows enlarged ventricles. Which treatment is usual? MedlinePlus Medical Encyclopedia, "Normal pressure hydrocephalus", Symptoms; Treatment. Outline: NBME Psychiatry Subject Exam content outline, Nervous System & Special Senses.
  • Two days after hip surgery, an 81-year-old woman who was independent at home is alert each morning and confused by night, drifting between drowsiness and agitation. She cannot say where she is. What is the most likely diagnosis? MedlinePlus Medical Encyclopedia, "Delirium", opening; Causes; Symptoms. Outline: NBME Psychiatry Subject Exam content outline, Nervous System & Special Senses.
  • Which microscopic brain changes are associated with Alzheimer disease? MedlinePlus Medical Encyclopedia, "Alzheimer disease", Causes. Outline: NBME Psychiatry Subject Exam content outline, Nervous System & Special Senses.

Other systems 4

  • A 19-year-old man has new personality change, a tremor and abnormal liver tests. A slit-lamp exam shows a brown ring around each iris. Which substance has built up in his tissues? MedlinePlus Medical Encyclopedia, "Wilson disease", opening; Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Other Systems, including Multisystem Processes & Disorders.
  • A 38-year-old man is referred for panic attacks. During each spell he has a headache, palpitations and sweating, and his blood pressure is 210/120. Between spells he feels well. Which test is most appropriate? MedlinePlus Medical Encyclopedia, "Pheochromocytoma", Symptoms; Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Other Systems, including Multisystem Processes & Disorders.
  • A 47-year-old woman is referred for depression. She also reports constipation, weight gain, heavy periods, dry skin and feeling cold when others are warm. Which test should be ordered first? MedlinePlus Medical Encyclopedia, "Hypothyroidism", Symptoms; Exams and Tests. Outline: NBME Psychiatry Subject Exam content outline, Other Systems, including Multisystem Processes & Disorders.
  • Five days after starting high-dose prednisone for asthma, a 45-year-old woman with no psychiatric history is euphoric, sleeps 2 hours a night and talks nonstop. What most likely triggered the episode? MedlinePlus Medical Encyclopedia, "Bipolar disorder", Causes. Outline: NBME Psychiatry Subject Exam content outline, Other Systems, including Multisystem Processes & Disorders.

Social sciences 3

  • A patient tells his psychiatrist that he has bought a gun and will shoot a named coworker tomorrow. Under the HIPAA Privacy Rule, which disclosure is permitted? HIPAA Privacy Rule, 45 CFR 164.512, paragraph (j). Outline: NBME Psychiatry Subject Exam content outline, Social Sciences.
  • A psychiatry resident and a current patient are attracted to each other, and the patient suggests a date. What does the AMA Code of Medical Ethics say? AMA Code of Medical Ethics, Opinion 9.1.1, Romantic or Sexual Relationships with Patients. Outline: NBME Psychiatry Subject Exam content outline, Social Sciences.
  • Before starting a new medicine, a psychiatrist explains the illness, the treatment, its risks and the other options. Which step helps confirm that the patient understood? MedlinePlus Medical Encyclopedia, "Informed consent - adults", What Should Occur During the Informed Consent Process?. Outline: NBME Psychiatry Subject Exam content outline, Social Sciences.

How this list was compiled: Our own questions, written to the content outline of the Psychiatry Subject Exam that NBME publishes (https://www.nbme.org/institutions/assess-learn/subject-exams/clinical-science/psychiatry/, read 2026-10-12). Systems and their ranges: General Principles, Including Normal Age-Related Findings and Care of the Well Patient 5-10%, Behavioral Health 65-70%, Nervous System & Special Senses 10-15%, Other Systems, including Multisystem Processes & Disorders 5-10%, Social Sciences 1-5%. The bank holds 4, 33, 6, 4 and 3 questions in that order, 50 in all; the 33 on behavioral health are filed under the outline's own list of topics. Every fact was read on 2026-10-12 in the public page the question names: the MedlinePlus Medical Encyclopedia and MedlinePlus Drug Information (National Library of Medicine), the US Preventive Services Task Force, the HIPAA Privacy Rule in the eCFR and the AMA Code of Medical Ethics. Licence: Questions, choices and explanations are original work of this site.

How it works

This free NBME psychiatry shelf practice exam has 50 patient vignettes of our own for the Psychiatry Subject Exam. It is unofficial practice, not affiliated with the National Board of Medical Examiners (NBME) and not endorsed by it.

Read the full guide

What the psychiatry shelf covers

NBME's Psychiatry Subject Exam content outline, read October 12, 2026, gives behavioral health 65 to 70%, the nervous system 10 to 15%, general principles and other systems 5 to 10% each, and social sciences 1 to 5%. The bank holds 33, 6, 4, 4 and 3 questions for those.

Using it as a psychiatry shelf exam study guide

The questions are filed under the outline's own headings for behavioral health: psychotic, anxiety and mood disorders, somatic and factitious disorders, eating disorders, childhood disorders, personality disorders, substance use and adverse effects of drugs. Each of those explanations rests on a named MedlinePlus section.

Timing

The timed test here asks 40 questions in 60 minutes: the minute and a half each that NBME's timing chart allows.

  • Durations decide many diagnoses in this bank: less than a month, at least 30 days, at least 6 months, at least 2 years.

Questions and answers

How many questions are on the NBME psychiatry shelf exam?

110 items in 2 hours 45 minutes, by the Subject Examination Timing Chart dated July 2021 on nbme.org. The chart notes that every web exam starts with a tutorial, which adds 15 minutes.

Are these real NBME psychiatry shelf questions?

No. All 50 vignettes are our own, written from the public content outline and public health pages. NBME's sample items and self-assessments were not opened or used, and none is reworded here.

Is there a passing score for the psychiatry shelf exam?

The outline and the timing chart print none. NBME says educators typically use these subject exams to assess students at the end of clerkships, so your clerkship decides how the score counts.